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At Fluxion, we’re passionate about delivering cell-based and cell-free solutions that facilitate the transformation of research discoveries into new ways to diagnose and treat patients. By characterizing molecular and cellular mechanisms of disease, Fluxion’s platforms help bridge the translational medicine gap, enabling rapid advances in disease research, drug discovery, and the development of diagnostic tests.

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Fluxion Launches New Dual Gas Option for BioFlux Controllers

New controller option allows control of 2 independent gas inputs for developing gas concentration gradients

Alameda, CA, September 1, 2018 - Fluxion Biosciences, a leading developer of automated solutions for cellular analysis in life sciences research and drug discovery, today announced that it has launched a new BioFlux capability for dual gas control.

Under normal physiological conditions, oxygen plays an essential role in a host of cellular processes such as metabolism, cell growth, differentiation and DNA metabolism. The concentration of oxygen can vary significantly between different tissues and organs such as the lung parenchyma (4-14%), liver (4-14%), kidney (4-14%), heart (4-14%), brain (0.5-8%), eye (1- 5%) and bone marrow (1-6%). Moreover, once inspired air enters the lung and oxygen is transferred to the blood via the alveolar capillaries, the oxygen concentration gradually falls to hypoxic levels. This illustrates the importance of controlling the oxygen concentration, and establishing an oxygen concentration gradient that better reflects the in vivo environment.

The dual-gas option for BioFlux controls allows researchers to model these processes by establishing a gas gradient across the flow channel. The dual gas controller provides the only commercially available shear flow system that gives the researcher the ability to immediately modify the oxygen concentration along a gradient, using our proprietary BioFlux Well Plate MicroFluidics technology. The system uses two input wells held at differing gas concentration levels. They both feed into a viewing area where users can establish gradients in the viewing region or switch between the two solutions.

The new dual-gas option is available on BioFlux 200, BioFlux DCIS, and BioFlux 1000Z systems.